This composition contains ceftriaxone and Sulbactum which are used for the treatment of bacterial infections such as skin, female reproductive organs and of stomach area.
Intra-abdominal infections
Community acquired pneumonia
Epiglottitis
Salmonella typhi infection
Septic arthritis
Uncomplicated gonorrhoea
Ceftriaxone inhibits the synthesis of mucopeptide present in the cell wall. they inhibit the carboxypeptidases and endopeptidases enzymes they play role in important cell wall and cell division therefore leads to cell death.
Sulbactum inhibits the beta-lactamase enzyme of the bacteria which is responsible for the development of resistance and prevents the reduction in activity of bacteria.
Ceftriaxone-
It is absorbed orally to lesser extent and absorbed mainly intravenously
It shows 95% of protein binding
It is excreted via urine
Sulbactum-
It is absorbed orally
It shows 38% serum proteins binding
It is excreted via urine
Common side effects of the injection includes:
Rashes
Diarrhoea
Nausea
Vomiting
Blood clots
Dizziness
Headache
Contraindicated in people with known hypersensitivity
Furosemide
Lidocaine
Metronidazole
Cefuroxime
| Ceftriaxone Sodium | 250 mg |
| Sulbactum | 125 mg |